Epigenetic assimilation in the aging human brain

BACKGROUND: Epigenetic drift progressively increases variation in DNA modification profiles of aging cells, but the finale of such divergence remains elusive. In this study, we explored the dynamics of DNA modification and transcription in the later stages of human life. RESULTS: We find that brain...

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Publicado en:Genome Biol
Main Authors: Oh, Gabriel, Ebrahimi, Sasha, Wang, Sun-Chong, Cortese, Rene, Kaminsky, Zachary A., Gottesman, Irving I., Burke, James R., Plassman, Brenda L., Petronis, Art
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848814/
https://ncbi.nlm.nih.gov/pubmed/27122015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0946-8
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