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A randomized, double-blind, placebo-controlled phase 2 pilot trial evaluating a novel, vaginal softgel capsule containing solubilized estradiol

OBJECTIVE: The aim of the study was to evaluate the safety and efficacy of vaginal estradiol (E(2)) softgel capsules for moderate-to-severe symptoms of vulvar and vaginal atrophy (VVA). Previous phase 1 studies showed lower systemic estrogen concentrations with this softgel capsule compared with an...

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Detalhes bibliográficos
Publicado no:Menopause
Main Authors: Pickar, James H., Amadio, Julia M., Hill, John M., Bernick, Brian A., Mirkin, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott-Raven Publishers 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848733/
https://ncbi.nlm.nih.gov/pubmed/26836245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000000592
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