Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress and Neuroinflammation

Doxorubicin (DOX) is a chemotherapeutic agent widely used in human malignancies. Its long-term use can cause neurobiological side-effects associated with depression. Omega-3 polyunsaturated fatty acids (ω-3 PUFAs), the essential fatty acids found in fish oil, possess neuroprotecitve and antidepressa...

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Publicat a:Nutrients
Autors principals: Wu, Yan-Qin, Dang, Rui-Li, Tang, Mi-Mi, Cai, Hua-Lin, Li, Huan-De, Liao, De-Hua, He, Xin, Cao, Ling-Juan, Xue, Ying, Jiang, Pei
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848711/
https://ncbi.nlm.nih.gov/pubmed/27120616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu8040243
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