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Host gene constraints and genomic context impact the expression and evolution of human microRNAs
Increasing evidence has shown that recent miRNAs tend to emerge within coding genes. Here we conjecture that human miRNA evolution is tightly influenced by the genomic context, especially by host genes. Our findings show a preferential emergence of intragenic miRNAs within old genes. We found that m...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848552/ https://ncbi.nlm.nih.gov/pubmed/27109497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11438 |
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