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MTG2: an efficient algorithm for multivariate linear mixed model analysis based on genomic information

Summary: We have developed an algorithm for genetic analysis of complex traits using genome-wide SNPs in a linear mixed model framework. Compared to current standard REML software based on the mixed model equation, our method is substantially faster. The advantage is largest when there is only a sin...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Lee, S. H., van der Werf, J. H. J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848406/
https://ncbi.nlm.nih.gov/pubmed/26755623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw012
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