A Multi-Component Prime-Boost Vaccination Regimen with a Consensus MOMP Antigen Enhances Chlamydia trachomatis Clearance

BACKGROUND: A vaccine for Chlamydia trachomatis is of urgent medical need. We explored bioinformatic approaches to generate an immunogen against C. trachomatis that would induce cross-serovar T-cell responses as (i) CD4(+) T cells have been shown in animal models and human studies to be important in...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Badamchi-Zadeh, Alexander, McKay, Paul F., Korber, Bette T., Barinaga, Guillermo, Walters, Adam A., Nunes, Alexandra, Gomes, João Paulo, Follmann, Frank, Tregoning, John S., Shattock, Robin J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848310/
https://ncbi.nlm.nih.gov/pubmed/27199987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00162
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