Histone deacetylase mediated silencing of AMWAP expression contributes to cisplatin nephrotoxicity

Cisplatin-induced acute kidney injury is a serious problem in cancer patients during treatment of solid tumors. Currently, there are no therapies available to treat or prevent cisplatin nephrotoxicity. Since histone deacetylase (HDAC) inhibition augments cisplatin anti-tumor activity, we tested whet...

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Vydáno v:Kidney Int
Hlavní autoři: Ranganathan, Punithavathi, Hamad, Rania, Mohamed, Riyaz, Jayakumar, Calpurnia, Muthusamy, Thangaraju, Ramesh, Ganesan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848209/
https://ncbi.nlm.nih.gov/pubmed/26509586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.326
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