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The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia

While the specific trigger of Parkinson Disease (PD) in most patients is unknown, considerable evidence suggests that the neuroinflammatory response makes an essential contribution to the neurodegenerative process. Drugs targeting metabotropic glutamate receptors (mGlu receptors), 7 Transmembrane (7...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Ponnazhagan, Ranjani, Harms, Ashley S., Thome, Aaron D., Jurkuvenaite, Asta, Gogliotti, Rocco, Niswender, Colleen M., Conn, P. Jeffrey, Standaert, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848139/
https://ncbi.nlm.nih.gov/pubmed/26872456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9655-z
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