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Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability
The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnormal and wild-type mRNAs. NMD is essential for viability in most organisms, but the molecular basis for this requirement is unknown. Here we show that a single, conserved NMD target, the mRNA coding for the stress response...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848089/ https://ncbi.nlm.nih.gov/pubmed/26952209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12876 |
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