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A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter
Cellular immunity against viral infection and tumor cells depends on antigen presentation by the major histocompatibility complex class 1 molecules (MHC I). Intracellular antigenic peptides are transported into the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP...
Enregistré dans:
| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848044/ https://ncbi.nlm.nih.gov/pubmed/26789246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16506 |
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