Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor

Poly (ADP) ribose polymerase (PARP) inhibitors, first evaluated nearly a decade ago, are primarily used in malignancies with known defects in DNA repair genes, such as alterations in breast cancer, early onset 1/2 (BRCA1/2). While no specific mutations in BRCA1/2 have been reported in malignant peri...

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Vydáno v:Cancer Biol Ther
Hlavní autoři: Kivlin, Christine M., Watson, Kelsey L., Al Sannaa, Ghadah A., Belousov, Roman, Ingram, Davis R., Huang, Kai-Lieh, May, Caitlin D., Bolshakov, Svetlana, Landers, Sharon M., Kalam, Azad Abul, Slopis, John M., McCutcheon, Ian E., Pollock, Raphael E., Lev, Dina, Lazar, Alexander J., Torres, Keila E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847988/
https://ncbi.nlm.nih.gov/pubmed/26650448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1108486
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