Regorafenib with a fluoropyrimidine for metastatic colorectal cancer after progression on multiple 5-FU-containing combination therapies and regorafenib monotherapy

We present 2 patients with metastatic colorectal cancer who had progressed despite treatment with first-line FOLFOX and second-line FOLFIRI combination chemotherapy regimens. After failing these fluoropyrimidine-based regimens, both patients received additional cytotoxic and targeted therapies with...

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Publicat a:Cancer Biol Ther
Autors principals: Marks, Eric I., Tan, Carlyn, Zhang, Jun, Zhou, Lanlan, Yang, Zhaohai, Scicchitano, Angelique, El-Deiry, Wafik S.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Bedside to Bench Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847811/
https://ncbi.nlm.nih.gov/pubmed/26561209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1113355
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