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Nitrated Fatty Acids Reverse Cigarette Smoke-Induced Alveolar Macrophage Activation and Inhibit Protease Activity via Electrophilic S-Alkylation

Nitrated fatty acids (NFAs), endogenous products of nonenzymatic reactions of NO-derived reactive nitrogen species with unsaturated fatty acids, exhibit substantial anti-inflammatory activities. They are both reversible electrophiles and peroxisome proliferator-activated receptor γ (PPARγ) agonists,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Reddy, Aravind T., Lakshmi, Sowmya P., Muchumarri, Ramamohan R., Reddy, Raju C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847772/
https://ncbi.nlm.nih.gov/pubmed/27119365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153336
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