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Statins inhibit blastocyst formation by preventing geranylgeranylation
STUDY HYPOTHESIS: Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase of the mevalonate pathway and prescription drugs that treat hypercholesterolemia, compromise preimplantation mouse development via modulation of HIPPO signaling. STUDY FINDING: HMG-CoA reductase activi...
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| Publicado no: | Mol Hum Reprod |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847613/ https://ncbi.nlm.nih.gov/pubmed/26908642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gaw011 |
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