Methamphetamine alters microglial immune function through P2X7R signaling

BACKGROUND: Purinoceptors have emerged as mediators of chronic inflammation and neurodegenerative processes. The ionotropic purinoceptor P2X7 (P2X7R) is known to modulate proinflammatory signaling and integrate neuronal-glial circuits. Evidence of P2X7R involvement in neurodegeneration, chronic pain...

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Bibliografiska uppgifter
I publikationen:J Neuroinflammation
Huvudupphovsmän: Fernandes, Nicole C., Sriram, Uma, Gofman, Larisa, Cenna, Jonathan M., Ramirez, Servio H., Potula, Raghava
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847215/
https://ncbi.nlm.nih.gov/pubmed/27117066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0553-3
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