Tighter αC-helix–αL16-helix interactions seem to make p38α less prone to activation by autophosphorylation than Hog1

Many eukaryotic protein kinases (EPKs) are autoactivated through autophosphorylation of their activation loop. Mitogen-activated protein (MAP) kinases do not autophosphorylate spontaneously; relying instead upon mitogen-activated protein kinase (MAPK) kinases (MKKs) for their activation loop phospho...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Tesker, Masha, Selamat, Sadiduddin Edbe, Beenstock, Jonah, Hayouka, Ruchama, Livnah, Oded, Engelberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
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Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847175/
https://ncbi.nlm.nih.gov/pubmed/26987986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160020
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