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Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase
Binary systems based on site-specific recombination have been used for tumor specific transcription targeting of suicide genes in animal models. In these binary systems a site specific recombinase or integrase that is expressed from a tumor specific promoter drives tumor specific expression of a cyt...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846993/ https://ncbi.nlm.nih.gov/pubmed/27117628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24971 |
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