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Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer

Cancer stem cells (CSCs) are responsible for the tumorigenesis and recurrence, so targeting CSCs is a potential effective method to cure cancers. Activated Hedgehog signaling pathway has been proved to be implicated in the maintenance of self-renewal of CSCs, and arsenic trioxide (As(2)O(3)) has bee...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Chang, Ke-Jie, Yang, Meng-Hang, Zheng, Jin-Cheng, Li, Bing, Nie, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846956/
https://ncbi.nlm.nih.gov/pubmed/27158399
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