Polydatin promotes apoptosis through upregulation the ratio of Bax/Bcl-2 and inhibits proliferation by attenuating the β-catenin signaling in human osteosarcoma cells

Osteosarcoma is the most prevalent primary malignant bone tumor mainly endangering young adults. In this study, we explore whether polydatin (PD), a glycoside form of resveratrol, is effective for osteosarcoma. Our results showed that PD dose-dependently inhibited proliferation and promoted apoptosi...

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Publicado en:Am J Transl Res
Autores principales: Xu, Ge, Kuang, Ge, Jiang, Wengao, Jiang, Rong, Jiang, Dianming
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846936/
https://ncbi.nlm.nih.gov/pubmed/27158379
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