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Prolonged survival with erlotinib followed by afatinib in a caucasian smoker with metastatic, poorly differentiated large cell carcinoma of the lung: a case report
Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR; ErbB1) – either exon 19 deletions or exon 21 point mutations – are associated with hypersensitivity to EGFR tyrosine kinase inhibitors (TKIs). EGFR mutations are more frequently found in females, non-sm...
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| Udgivet i: | Cancer Biol Ther |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846105/ https://ncbi.nlm.nih.gov/pubmed/26186355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070993 |
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