A potentially critical Hpa II site of the X chromosome-linked PGK1 gene is unmethylated prior to the onset of meiosis of human oogenic cells.

Hpa II site H8 is in the CpG-rich 5' untranslated region of the human X chromosome-linked gene for phosphoglycerate kinase 1 (PGK1). It is the only Hpa II site in the CpG "island" whose methylation pattern is perfectly correlated with transcriptional silence of this gene. We measured DNA methylation...

Description complète

Détails bibliographiques

Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Singer-Sam, J, Goldstein, L, Dai, A, Gartler, S M, Riggs, A D
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48461/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1371357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1413
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!