Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype

Multiple juxtacrine and paracrine interactions occur between cancer cells and non-cancer cells of the tumor microenvironment (TME) that direct tumor progression. Cancer Associated Fibroblasts (CAFs) are an integral component of the TME, and the majority of breast tumor stroma is comprised of CAFs. H...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Shah, Sanket H, Miller, Philip, Garcia-Contreras, Marta, Ao, Zheng, Machlin, Leah, Issa, Emilio, El-Ashry, Dorraya
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846097/
https://ncbi.nlm.nih.gov/pubmed/26186233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1071742
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