Prevention of COPD exacerbation by lysozyme: a double-blind, randomized, placebo-controlled study

BACKGROUND/AIM: Lysozyme (mucopeptide N-acetyl-muramyl hydrolase) is widely used as a mucolytic and anti-inflammatory agent in Japan. We evaluated the effects of long-term lysozyme administration on COPD exacerbation. METHODS: In a 1-year, randomized, double-blind, placebo-controlled, parallel trial...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Fukuchi, Yoshinosuke, Tatsumi, Koichiro, Inoue, Hiromasa, Sakata, Yukinori, Shibata, Kai, Miyagishi, Hideaki, Marukawa, Yasuhiro, Ichinose, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846053/
https://ncbi.nlm.nih.gov/pubmed/27143873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S103105
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