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Small molecules in the cone snail arsenal

Cone snails are renowned for producing peptide-based venoms, the conopeptides and conotoxins, to capture their prey animals. Here, we show that small molecules also contribute to the activity of the venoms. A novel guanine derivative, genuanine, causes paralysis in mice and is found in the venoms of...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Neves, Jorge L.B., Lin, Zhenjian, Imperial, Julita S., Antunes, Agostinho, Vasconcelos, Vitor, Olivera, Bal-domero M., Schmidt, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845746/
https://ncbi.nlm.nih.gov/pubmed/26421741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b02389
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