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Epistatic interaction between COMT and DTNBP1 modulates prefrontal function in mice and in humans

Cognitive functions are highly heritable and the impact of complex genetic interactions, though undoubtedly important, has received little investigation. Here we show in an animal model and in a human neuroimaging experiment a consistent non-linear interaction between two genes—catechol-O-methyl tra...

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Foilsithe in:Mol Psychiatry
Main Authors: Papaleo, F, Burdick, MC, Callicott, JH, Weinberger, DR
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845721/
https://ncbi.nlm.nih.gov/pubmed/24145376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.133
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