Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations

Objective: The latest nonnucleoside reverse transcriptase inhibitor (NNRTI) rilpivirine (RPV) is indicated for human immunodeficiency virus type-1 (HIV-1) patients initiating antiretroviral treatment, but the extent of genotypic RPV resistance in treatment-naive patients outside clinical trials is p...

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Bibliographische Detailangaben
Veröffentlicht in:AIDS Res Hum Retroviruses
Hauptverfasser: Theys, Kristof, Van Laethem, Kristel, Gomes, Perpetua, Baele, Guy, Pineda-Peña, Andrea-Clemencia, Vandamme, Anne-Mieke, Camacho, Ricardo J., Abecasis, Ana B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2016
Schlagworte:
Epidemiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845676/
https://ncbi.nlm.nih.gov/pubmed/26651266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0095
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