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Structural and Functional Abnormalities of the Neuromuscular Junction in the Trembler-J Homozygote Mouse Model of Congenital Hypomyelinating Neuropathy

Mutations in peripheral myelin protein 22 (PMP22) result in the most common form of Charcot-Marie-Tooth (CMT) disease, CMT1A. This hereditary peripheral neuropathy is characterized by dysmyelination of peripheral nerves, reduced nerve conduction velocity, and muscle weakness. A PMP22 point mutation...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Scurry, Alexandra N., Heredia, Dante J., Feng, Cheng-Yuan, Gephart, Gregory B., Hennig, Grant W., Gould, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845671/
https://ncbi.nlm.nih.gov/pubmed/26921370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlw004
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