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Mutations in ribosomal proteins: Apoptosis, cell competition, and cancer

Mutations affecting multiple ribosomal proteins are implicated in cancer. Using genetic mosaics in the fruit fly Drosophila, we describe 3 apoptotic mechanisms that affect Rp/Rp homozygous mutant cells, Rp/+ heterozygous cells, or Rp/+ heterozygous cells in competition with nearby wild type cells, a...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Baker, Nicholas E., Kale, Abhijit
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845181/
https://ncbi.nlm.nih.gov/pubmed/27308545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1029065
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