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Regulation of hematopoietic progenitors by estrogens as a basis for new antileukemic strategies

We recently reported that estrogens regulate survival, proliferation, and self-renewal of hematopoietic stem cells and progenitors via estrogen receptor-α activation. Through its proapoptotic effect on malignant progenitors, tamoxifen treatment blocks the development of JAK2(V617F)-induced myeloprol...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Oncol
Autori principali: Sánchez-Aguilera, Abel, Méndez-Ferrer, Simón
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845161/
https://ncbi.nlm.nih.gov/pubmed/27308525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1009728
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