Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair

Notch has a well-defined role in controlling cell fate decisions in the embryo and the adult epidermis and immune systems, yet emerging evidence suggests Notch also directs non-cell-autonomous signalling in adult tissues. Here, we show that Notch1 works as a damage response signal. Epidermal Notch i...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Li, Zhi, Hodgkinson, Tom, Gothard, Elizabeth J., Boroumand, Soulmaz, Lamb, Rebecca, Cummins, Ian, Narang, Priyanka, Sawtell, Amy, Coles, Jenny, Leonov, German, Reboldi, Andrea, Buckley, Christopher D., Cupedo, Tom, Siebel, Christian, Bayat, Ardeshir, Coles, Mark C., Ambler, Carrie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844683/
https://ncbi.nlm.nih.gov/pubmed/27099134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11394
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