Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner

Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice. Previous studies indicated that VM cells were the result of homeostatic proliferation (HP) resembling the proliferation observed in a lymphopenic environment. Here we demo...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: White, Jason T., Cross, Eric W., Burchill, Matthew A., Danhorn, Thomas, McCarter, Martin D., Rosen, Hugo R., O'Connor, Brian, Kedl, Ross M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844673/
https://ncbi.nlm.nih.gov/pubmed/27097762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11291
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