A Genome-Wide Identified Risk Variant for PTSD is a Methylation Quantitative Trait Locus and Confers Decreased Cortical Activation to Fearful Faces

Genetic factors appear to be highly relevant to predicting differential risk for the development of post-traumatic stress disorder (PTSD). In a discovery sample, we conducted a genome-wide association study (GWAS) for PTSD using a small military cohort (Systems Biology PTSD Biomarkers Consortium; SB...

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Veröffentlicht in:Am J Med Genet B Neuropsychiatr Genet
Hauptverfasser: Almli, Lynn M., Stevens, Jennifer S., Smith, Alicia K., Kilaru, Varun, Meng, Qian, Flory, Janine, Abu-Amara, Duna, Hammamieh, Rasha, Yang, Ruoting, Mercer, Kristina B., Binder, Elizabeth B., Bradley, Bekh, Hamilton, Steven, Jett, Marti, Yehuda, Rachel, Marmar, Charles R., Ressler, Kerry J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844461/
https://ncbi.nlm.nih.gov/pubmed/25988933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32315
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