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Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes

The discovery of JAK2(V617F) a decade ago led to optimism for a rapidly developing treatment revolution in Ph(−) myeloproliferative neoplasms. Unlike BCR–ABL, however, JAK2 was found to have a more heterogeneous role in carcinogenesis. Therefore, for years, development of new therapies was slow, des...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Sochacki, Andrew L, Fischer, Melissa A, Savona, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844455/
https://ncbi.nlm.nih.gov/pubmed/27143923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S83868
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