Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer

Loss of 3p11-p14 is a frequent event in epithelial cancer and a candidate prognostic biomarker in cervical cancer. In addition to loss, promoter methylation can participate in gene silencing and promote tumor aggressiveness. We have performed a complete mapping of promoter methylation at 3p11-p14 in...

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Publicat a:Epigenetics
Autors principals: Lando, Malin, Fjeldbo, Christina S, Wilting, Saskia M, Snoek, Barbara C, Aarnes, Eva-Katrine, Forsberg, Malin F, Kristensen, Gunnar B, Steenbergen, Renske DM, Lyng, Heidi
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844207/
https://ncbi.nlm.nih.gov/pubmed/26291246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1085140
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