Citrullination regulates pluripotency and histone H1 binding to chromatin

Citrullination is the post-translational conversion of an arginine residue within a protein to the non-coded amino acid citrulline(1). This modification leads to the loss of a positive charge and reduction in hydrogen bonding ability. It is carried out by a small family of tissue-specific vertebrate...

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Pubblicato in:Nature
Autori principali: Christophorou, Maria A., Castelo-Branco, Gonçalo, Halley-Stott, Richard P., Slade Oliveira, Clara, Loos, Remco, Radzisheuskaya, Aliaksandra, Mowen, Kerri A., Bertone, Paul, Silva, José, Zernicka-Goetz, Magdalena, Nielsen, Michael L., Gurdon, John, Kouzarides, Tony
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843970/
https://ncbi.nlm.nih.gov/pubmed/24463520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12942
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