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Population-based analysis of Actinobacillus pleuropneumoniae ApxIVA for use as a DIVA antigen

APXIVA is an RTX toxin of Actinobacillus pleuropneumoniae that is a candidate antigen to differentiate infected from vaccinated animals (DIVA). Insertion of ISApl1 into the apxIVA gene is known to compromise an APXIVA-based DIVA approach, as is potentially a TGG to TGA mutation in the apxIVA gene. I...

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Detalles Bibliográficos
Publicado en:Vaccine
Main Authors: O’Neilla, Ciaragh, Jones, Sophie C.P., Bossé, Janine T., Watson, Conrad M., Williamson, Susanna M., Rycroft, Andrew N., Simon Kroll, J., Hartley, Helen M., Langford, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843962/
https://ncbi.nlm.nih.gov/pubmed/20483193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.04.113
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