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Expression of the Helicobacter pylori virulence factor vacuolating cytotoxin A (vac A) is influenced by a potential stem‐loop structure in the 5′ untranslated region of the transcript

The vacuolating cytotoxin, VacA, is an important virulence factor secreted by the gastric pathogen H elicobacter pylori. Certain vac A genotypes are strongly associated with disease risk, but the association is not absolute. The factors determining vac A gene expression are not fully understood, and...

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Dettagli Bibliografici
Pubblicato in:Mol Microbiol
Autori principali: Amilon, Karin R., Letley, Darren P., Winter, Jody A., Robinson, Karen, Atherton, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843948/
https://ncbi.nlm.nih.gov/pubmed/26259667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13160
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