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The evolutionary divergence of TRPA1 channel: heat-sensitive, cold-sensitive and temperature-insensitive

The Transient Receptor Potential Ankyrin 1 ion channel is heat-sensitive in invertebrate and ancestral vertebrates, cold-sensitive in rodents, and temperature-insensitive in primates. This remarkable divergence in temperature sensitivity is in contrast to its role in sensing electrophilic compounds,...

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Bibliografiske detaljer
Udgivet i:Temperature (Austin)
Hovedforfatter: Chen, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843899/
https://ncbi.nlm.nih.gov/pubmed/27227016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23328940.2014.998903
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