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The evolutionary divergence of TRPA1 channel: heat-sensitive, cold-sensitive and temperature-insensitive
The Transient Receptor Potential Ankyrin 1 ion channel is heat-sensitive in invertebrate and ancestral vertebrates, cold-sensitive in rodents, and temperature-insensitive in primates. This remarkable divergence in temperature sensitivity is in contrast to its role in sensing electrophilic compounds,...
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Udgivet i: | Temperature (Austin) |
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Hovedforfatter: | |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Taylor & Francis
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843899/ https://ncbi.nlm.nih.gov/pubmed/27227016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23328940.2014.998903 |
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