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Synthesis of Enantioenriched Indolines by a Conjugate Addition/Asymmetric Protonation/Aza-Prins Cascade Reaction

A conjugate addition/asymmetric protonation/aza-Prins cascade reaction has been developed for the enantioselective synthesis of fused polycyclic indolines. A catalyst system generated from ZrCl(4) and 3,3’-dibromo-BINOL enables the synthesis of a range of polycyclic indolines in good yields and high...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Daniels, Blake E., Ni, Jane, Reisman, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843768/
https://ncbi.nlm.nih.gov/pubmed/26844668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510972
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