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TLR2 and TLR4 expression and inflammatory cytokines are altered in the airway epithelium of those with alcohol use disorders

BACKGROUND: The lung has a highly regulated system of innate immunity to protect itself from inhaled microbes and toxins. The first line of defense is mucociliary clearance, but if invaders overcome this, inflammatory pathways are activated. Toll-like receptors (TLRs) are expressed on the airway epi...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Bailey, KL, Romberger, DJ, Katafiasz, DM, Heires, AJ, Sisson, JH, Wyatt, TA, Burnham, EL
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843766/
https://ncbi.nlm.nih.gov/pubmed/26208141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12803
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