Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote‐Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction

BACKGROUND: Ivabradine selectively inhibits the pacemaker current of the sinoatrial node, slowing heart rate. Few studies have examined the effects of ivabradine on the mechanical properties of the heart after reperfused myocardial infarction (MI). Advances in ultrasound speckle‐tracking allow strai...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: O'Connor, Daniel M., Smith, Robert S., Piras, Bryan A., Beyers, Ronald J., Lin, Dan, Hossack, John A., French, Brent A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843531/
https://ncbi.nlm.nih.gov/pubmed/27107133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002989
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