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Mechanism for accurate, protein-assisted DNA annealing by Deinococcus radiodurans DdrB

Accurate pairing of DNA strands is essential for repair of DNA double-strand breaks (DSBs). How cells achieve accurate annealing when large regions of single-strand DNA are unpaired has remained unclear despite many efforts focused on understanding proteins, which mediate this process. Here we repor...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sugiman-Marangos, Seiji N., Weiss, Yoni M., Junop, Murray S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843489/
https://ncbi.nlm.nih.gov/pubmed/27044084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520847113
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