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Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation

The catheter-associated uropathogen Proteus mirabilis frequently causes urinary stones, but little has been known about the initial stages of bladder colonization and stone formation. We found that P. mirabilis rapidly invades the bladder urothelium, but generally fails to establish an intracellular...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Schaffer, Jessica N., Norsworthy, Allison N., Sun, Tung-Tien, Pearson, Melanie M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843424/
https://ncbi.nlm.nih.gov/pubmed/27044107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601720113
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