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Parenteral Nutrition Decreases Paneth cell function and Intestinal Bactericidal Activity while Increasing Susceptibility to Bacterial Enteroinvasion

INTRODUCTION: Parenteral nutrition (PN) increases the risk of infection in patients with contraindication to enteral feeding. Paneth cells produce and secrete antimicrobial products that protect the mucosa from pathogens. Their loss is associated with increased host-pathogen interactions, mucosal in...

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Detalhes bibliográficos
Publicado no:JPEN J Parenter Enteral Nutr
Main Authors: Heneghan, Aaron F, Pierre, Joseph F, Tandee, Kanokwan, Shanmuganayagam, Dhanansayan, Wang, Xinying, Reed, Jess D., Steele, James L, Kudsk, Kenneth A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843109/
https://ncbi.nlm.nih.gov/pubmed/23894173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0148607113497514
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