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Whi5 phosphorylation embedded in the G(1)/S network dynamically controls critical cell size and cell fate

In budding yeast, overcoming of a critical size to enter S phase and the mitosis/mating switch—two central cell fate events—take place in the G(1) phase of the cell cycle. Here we present a mathematical model of the basic molecular mechanism controlling the G(1)/S transition, whose major regulatory...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Palumbo, Pasquale, Vanoni, Marco, Cusimano, Valerio, Busti, Stefano, Marano, Francesca, Manes, Costanzo, Alberghina, Lilia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843020/
https://ncbi.nlm.nih.gov/pubmed/27094800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11372
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