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Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin

Accurate chromosome segregation during cell division is crucial for propagating life and protects from cellular transformation. The SKAP:Astrin heterodimer localizes to spindle microtubules and to mature microtubule–kinetochore attachments during mitosis. Depletion of either subunit disrupts spindle...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Friese, Alexandra, Faesen, Alex C., Huis in ‘t Veld, Pim J., Fischböck, Josef, Prumbaum, Daniel, Petrovic, Arsen, Raunser, Stefan, Herzog, Franz, Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843017/
https://ncbi.nlm.nih.gov/pubmed/27095104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11407
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