Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars

BACKGROUND AND PURPOSE: Sirtuin1 (SIRT1), the founding member of mammalian class III histone deacetylases, is reported to be a drug target involved in fibrotic diseases. However, whether it is an effective drug target in hypertrophic scar treatment is still not known. EXPERIMENTAL APPROACH: In the p...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Bai, Xiao‐Zhi, Liu, Jia‐Qi, Yang, Long‐Long, Fan, Lei, He, Ting, Su, Lin‐Lin, Shi, Ji‐Hong, Tang, Chao‐Wu, Zheng, Zhao, Hu, Da‐Hai
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842923/
https://ncbi.nlm.nih.gov/pubmed/26891034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13460
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