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AB268. Down-regulation XIAP expression enhances the sensitivity of RCC cells to apoptosis, but the basal expression of XIAP in apoptosis is stable

BACKGROUND: Dysregulation of apoptotic pathway plays a critical role in tumor progression and resistance to chemo-, immuno- and radio-therapy in human renal cell carcinoma (RCC). The X-linked Inhibitor of Apoptosis (XIAP), a key member of the Inhibitors of Apoptosis Protein (IAP) family, possesses t...

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Detalhes bibliográficos
Publicado no:Transl Androl Urol
Main Authors: Yang, Wenzheng, Yan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842595/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s268
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