AB251. 15-oxospiramilactone inhibits human renal cell carcinoma cell tumorigenesis through inhibition of Wnt/β-catenin signaling

BACKGROUND: Renal-cell carcinoma (RCC) is resistant to almost all chemotherapeutics and radiation therapy. Wnt/β-catenin signaling plays an important role in RCC tumorigenesis, a drug targeting the Wnt signaling is likely to have therapeutic benefit. 15-oxospiramilactone is a new Wnt molecule inhibi...

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Vydáno v:Transl Androl Urol
Hlavní autoři: Yi, Xiaoming, Shen, Tianyi, Zhou, Wenquan, Sang, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842552/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s251
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