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Cyclic AMP signaling restricts activation and promotes maturation and antioxidant defenses in astrocytes

BACKGROUND: cAMP signaling produces dramatic changes in astrocyte morphology and physiology. However, its involvement in phenotype acquisition and the transcriptionally mediated mechanisms of action are largely unknown. RESULTS: Here we analyzed the global transcriptome of cultured astroglial cells...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Genomics
Hauptverfasser: Paco, Sonia, Hummel, Manuela, Plá, Virginia, Sumoy, Lauro, Aguado, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842285/
https://ncbi.nlm.nih.gov/pubmed/27108081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2623-4
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